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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
人类
SEC63 - SEC63 Homolog, Protein Translocation Regulator
Alias:
ERdj2
PCLD2
SEC63L
DNAJC23
PRO2507
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
内质网膜上的蛋白质转运装置的核心组件是Sec61复合物。这个基因编码的蛋白质和SEC62蛋白质与无核糖体的Sec61复合物相关联。据推测,Sec61-Sec62-Sec63复合物可能将蛋白质进行翻译后的转运进入内质网。Sec61-Sec62-Sec63复合物还可能对受到泛素-蛋白酶体降解途径调控的内质网蛋白进行反向运输。这个基因编码的蛋白质是一个位于粗糙内质网上的整合膜蛋白。[RefSeq,2008年7月提供]
Related ID:
NCBI:11231
ENSEMBL:ENSG00000025796
HGNC:21082
UNIPROT:Q9UGP8
OMIM:608648
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
11231
3
21
90453 bp
88.00
377
4
5
15
SEC63 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
No data available
Transcripts & Proteins
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#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Reset
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available
Related Drugs
Name
CAS Number
Status
Phase
Link
No data available
References Literature
Title
PMID
Journal
Year
IF
No Data Found!
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