Log In|Sign Up
中文人类
DUSP10 - Dual Specificity Phosphatase 10
Alias:
MKP5
MKP-5
Favorite
双特异性的蛋白磷酸酶通过去除磷酸丝氨酸/苏氨酸和磷酸酪氨酸残基来失活其靶标激酶。它们负调控与细胞增殖和分化相关的MAP激酶超家族的成员。这个双特异性磷酸酶家族的不同成员对MAP激酶的底物特异性、不同的组织分布和亚细胞定位以及不同的细胞外刺激诱导的表达诱导模式表现出不同的特异性。这个基因产物与p38和SAPK/JNK结合并使其失活。可变剪接导致多个转录变异体。[RefSeq,2014年4月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
DUSP10 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
