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中文人类
LZTS1 - Leucine Zipper Tumor Suppressor 1
Alias:
F37
FEZ1
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这个基因编码一种在正常组织中普遍表达的肿瘤抑制蛋白。在眼黑色素瘤中，这种蛋白在快速转移和转移性肿瘤细胞中的表达被沉默，但在缓慢转移或不转移的肿瘤细胞中具有正常表达。这种蛋白可能与Cdk1/cyclinB1复合物相互作用，在细胞周期控制中发挥作用。这个基因位于染色体区域8p22上。8p臂的杂合性丢失（LOH）是许多类型癌症的共同特征。[RefSeq,2009年11月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
LZTS1 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
