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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
人类
CDC37 - Cell Division Cycle 37, HSP90 Cochaperone
Alias:
P50CDC37
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码的蛋白质与Cdc 37高度相似,Cdc 37是酿酒酵母细胞分裂周期调控蛋白。这个蛋白质是一种具有特定功能的分子伴侣,参与细胞信号传导。已经证明它可以与Hsp90和各种蛋白激酶(包括CDK4、CDK6、SRC、RAF-1、MOK以及eIF2α激酶)形成复合物。认为它在指导Hsp90到达其靶激酶方面起着关键作用。[RefSeq,2008年7月提供]
Related ID:
NCBI:11140
ENSEMBL:ENSG00000105401
HGNC:1735
UNIPROT:Q16543
OMIM:605065
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
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Reference
11140
1
8
12410 bp
44.47
12
--
3
23
CDC37 Genetics information (-)
GRCh38
Sequence Homology
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* This data comes from NCBI.
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