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中文人类
AKR1C4 - Aldo-keto Reductase Family 1 Member C4
Alias:
C11
CDR
DD4
CHDR
DD-4
HAKRA
3-alpha-HSD
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这个基因编码aldo/keto还原酶超家族的一员，该超家族由40多种已知的酶和蛋白质组成。这些酶通过利用NADH和/或NADPH作为辅因子，将醛和酮转化为它们相应的醇。这些酶具有重叠但不同的底物特异性。这个酶催化氯丹，一种有毒的有机氯农药，在肝脏中生物还原为氯丹醇。这个基因与其他三个基因成员具有高度的序列一致性，并与这些基因在染色体10p15-p14处聚类。[由RefSeq，2008年7月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
AKR1C4 Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
