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中文人类
DNAJB4 - DnaJ Heat Shock Protein Family (Hsp40) Member B4
Alias:
DjB4
HLJ1
DNAJW
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这个基因编码的蛋白质是一种分子伴侣、肿瘤抑制子，并属于热休克蛋白-40家族成员。编码的蛋白质结合细胞粘附蛋白E-钙粘蛋白，并将其定位到质膜上。这个蛋白质还可以结合错误折叠的E-钙粘蛋白，并将其定位到与内质网相关的降解部位。这个基因是结直肠癌的强有力肿瘤抑制子，其下调可能作为预测患者预后的良好生物标志物。已经发现这个基因有几个编码不同异型的转录变异体。[由RefSeq，2015年11月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
DNAJB4 Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
