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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
人类
UBE2C - Ubiquitin Conjugating Enzyme E2 C
Alias:
UBCH10
dJ447F3.2
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
泛素化修饰蛋白质是一种重要的细胞机制,用于靶向异常或短寿命蛋白质进行降解。泛素化涉及至少三类酶:泛素-活化酶,泛素-结合酶和泛素-蛋白连接酶。这个基因编码E2泛素-结合酶家族的一员。编码的蛋白质是破坏有丝分裂周期蛋白和细胞周期进展所必需的,可能涉及癌症进展。已发现这个基因的多个转录变异体,编码不同的异构体。这个基因的假基因位于染色体4,14,15,18和19上。[由RefSeq,2013年8月提供]
Related ID:
NCBI:11065
ENSEMBL:ENSG00000175063
HGNC:15937
UNIPROT:O00762
OMIM:605574
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
11065
6
6
4309 bp
19.65
4
--
5
16
UBE2C Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
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Transcripts & Proteins
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Transcript
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* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
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Cell-specific RNA expression
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References Literature
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