人类

WWP1 - WW Domain Containing E3 Ubiquitin Protein Ligase 1

Alias:
AIP5
Tiul1
hSDRP1
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
WW域含蛋白在所有真核生物中都有发现,并在蛋白质降解、转录和RNA剪接等多种细胞功能的调节中扮演重要角色。这个基因编码一个包含4个串联WW结构域和HECT(与E6相关蛋白羧基末端同源)结构域的蛋白质。编码的蛋白质属于NEDD4样蛋白质家族,它们是E3泛素连接酶分子,并调节包括将蛋白质靶向至蛋白酶体或溶酶体等关键转运决策。这个基因的可变剪接至少产生了6种转录变异体;然而,这些转录本的完整长度尚未确定。[由RefSeq,2008年7月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
10
25
125957 bp
105.20
7
--
8
17

WWP1 Genetics information (+)

GRCh38

Sequence Homology

Related Diseases and Mutations

#
Disease
Anatomical Category
Score
Mutations
No data available

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
Link
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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