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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Adarb1 - adenosine deaminase, RNA-specific, B1
Alias:
Red1
Adar2
D10Bwg0447e
1700057H01Rik
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
这个基因编码一种双链RNA特异性的腺苷脱氨酶,参与通过腺苷(A)向肌苷(I)的位点特异性转换编辑前mRNA。这种酶的底物包括离子型谷氨酸受体(GluR2-6)和血清素受体(5HT2C)。在啮齿动物中的研究表明,这种蛋白质可以通过A->I编辑修饰其自身的预mRNA,以创建一个新的可接受剪接位点,从而导致其蛋白质表达的下调。其他剪接事件导致编码不同异型体的转录变异体。[由RefSeq,2008年7月提供]
Related ID:
NCBI:110532
ENSEMBL:ENSMUSG00000020262
UNIPROT:Q91ZS8
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
110532
11
11
127565 bp
78.00
8
6
Adarb1 Genetics information (-)
GRCm39
Sequence Homology
Transcripts & Proteins
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CDS(bp)
Protein
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* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
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