人类

IL24 - Interleukin 24

Alias:
C49A
FISP
MDA7
MOB5
ST16
IL10B
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码细胞因子IL10家族的一员。它被鉴定为在黑色素瘤细胞终末分化期间诱导的基因。这个基因编码的蛋白质可以选择性地诱导各种癌细胞中的凋亡。这个基因的过度表达导致几个GADD家族基因的表达升高,这与凋亡的诱导相关。在黑色素瘤细胞中,发现这个基因可以诱导丝裂原活化蛋白激酶14(MAPK7/P38)和热休克27kDa蛋白1(HSPB2/HSP27)的磷酸化,但在正常的永生黑色素细胞中不被诱导。已经报道了一种替代剪接转录变异体,它编码不同的异构体。[由RefSeq,2008年7月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
7
7
6697 bp
23.82
7
--
5
13

IL24 Genetics information (+)

GRCh38

Sequence Homology

Related Diseases and Mutations

#
Disease
Anatomical Category
Score
Mutations
No data available

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
Link
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Comparison
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