Log In|Sign Up
中文人类
COPS5 - COP9 Signalosome Subunit 5
Alias:
CSN5
JAB1
SGN5
MOV-34
Favorite
这个基因编码的蛋白质是COP9信号体的八个亚基之一，COP9信号体是一个高度保守的蛋白质复合体，作为多个信号通路中的重要调节物。COP9信号体的结构和功能与26S蛋白酶体的19S调节颗粒相似。COP9信号体已被证明与SCF型E3泛素连接酶相互作用，并作为E3泛素连接酶的阳性调节物。该蛋白质据报道涉及细胞周期蛋白依赖性激酶抑制剂CDKN1B/p27Kip1的降解。据知，它还是一个增加JUN/AP1转录因子特异性的协同激活物。[由RefSeq，2008年7月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
COPS5 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
