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中文小鼠
F11 - coagulation factor XI
Alias:
FXI
PTA
Cf11
1600027G01Rik
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这个基因编码一种糖蛋白凝血因子，在血液凝固和止血的内在途径中扮演重要角色。编码的蛋白是一种无活性的酶原，可以通过凝血因子XIIa、thrombin或因子XIa激活，生成有活性的XIa蛋白酶。缺乏编码蛋白的小鼠在腹膜炎感染李斯特菌时显示出生存优势，并抵抗炎症和细菌感染。[RefSeq，2015年4月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
F11 Genetics information (-)
GRCm39
Sequence Homology
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
References Literature
Title
PMID
Journal
Year
IF
