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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
人类
STIP1 - Stress Induced Phosphoprotein 1
Alias:
HOP
P60
STI1
STI1L
HEL-S-94n
IEF-SSP-3521
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
STIP1 是一种调节蛋白,负责协调 HSP70(参见 HSPA1A;MIM 140550)和 HSP90(参见 HSP90AA1;MIM 140571)在蛋白质折叠中的作用。 通过结合 HSP90 和结合底物的 HSP70,被认为可以帮助蛋白质从 HSP70 转移到 HSP90。 STIP1 还刺激 HSP70 的 ATP 酶活性并抑制 HSP90 的 ATP 酶活性,表明它调节这些分子伴侣的构象和 ATP 酶周期(Song 和 Masison,2005 [PubMed 16100115])。[由 OMIM 在 2009 年 7 月提供]
Related ID:
NCBI:10963
ENSEMBL:ENSG00000168439
HGNC:11387
UNIPROT:P31948
OMIM:605063
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
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Reference
10963
3
14
19272 bp
62.64
11
--
4
28
STIP1 Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
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* This data comes from NCBI.
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