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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
人类
ME3 - Malic Enzyme 3
Alias:
NADP-ME
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
苹果酸酶使用NAD+或NADP+作为辅因子,催化苹果酸的氧化脱羧作用,生成丙酮酸。哺乳动物组织中包含3种不同的苹果酸酶同工型:一种胞质NADP+依赖型同工型,一种线粒体NADP+依赖型同工型,和一种线粒体NAD+依赖型同工型。这个基因编码一个线粒体NADP+依赖型同工型。已经发现了这个基因的多个可变剪接转录变异体,但一些变异体的生物学有效性尚未确定。[由RefSeq,2008年7月提供]
Related ID:
NCBI:10873
ENSEMBL:ENSG00000151376
HGNC:6985
UNIPROT:Q16798
OMIM:604626
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
10873
10
15
237687 bp
67.07
21
--
4
4
ME3 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
No data available
Transcripts & Proteins
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#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Reset
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available
Related Drugs
Name
CAS Number
Status
Phase
Link
No data available
References Literature
Title
PMID
Journal
Year
IF
No Data Found!
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