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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Foxp1 - forkhead box P1
Alias:
3110052D19Rik
4932443N09Rik
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
具有多种功能,包括DNA结合转录抑制活性,特异性地结合RNA聚合酶II;RNA聚合酶II的顺式调控区域序列特异性DNA结合活性;以及相同的蛋白质结合活性。参与T滤泡辅助细胞分化;运动神经元轴突引导;以及大分子代谢过程的正向调节。在几个过程的上游或内部发挥作用,包括动物器官发育;细胞群增殖的正向调节;以及RNA聚合酶II的转录调节。位于细胞核中。在几个结构中表达,包括消化系统;大脑;胚胎间充质;生殖泌尿系统;以及肌肉系统。这个基因的人类同源物与几种疾病有关,包括巴雷特食管;先天性心脏病;食管腺癌;智力障碍-严重语言延迟-轻度畸形综合征;以及腹膜炎。与人类FOXP1(翼状翅盒P1)正交。[由基因组资源联盟,2022年4月提供]
Related ID:
NCBI:108655
ENSEMBL:ENSMUSG00000030067
UNIPROT:P58462
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
108655
41
19
608285 bp
78.83
12
17
Foxp1 Genetics information (-)
GRCm39
Sequence Homology
Transcripts & Proteins
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#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
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Interactions
Reset
Acting
Regulation
Detail
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Target
Residues
Reference
Score
No data available
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Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available
References Literature
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PMID
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Year
IF
No Data Found!
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