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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Atic - 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
Alias:
2610509C24Rik
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
使IMP环化水解酶活性和磷酸核糖氨基咪唑甲酰胺甲酰转移酶活性得以实现。参与嘌呤核苷酸单磷酸生物合成过程。在细胞对白介素-7的响应中起上游作用或位于细胞内。位于线粒体中。在包括消化系统、心脏、神经系统、感觉器官和泌尿系统在内的几个结构中表达。该基因的人类同源物与嘌呤-嘧啶代谢紊乱有关。与人类ATIC(5-氨基咪唑-4-甲酰胺核苷酸甲酰转移酶/IMP环化水解酶)正交。[由基因组资源联盟,2022年4月提供]
Related ID:
NCBI:108147
ENSEMBL:ENSMUSG00000026192
UNIPROT:Q9CWJ9
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
108147
1
16
22248 bp
64.22
3
4
Atic Genetics information (+)
GRCm39
Sequence Homology
Transcripts & Proteins
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#
Transcript
Length(nt)
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* This data comes from NCBI.
Gene Expression
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Name
MGI
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