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中文小鼠
Xrcc4 - X-ray repair complementing defective repair in Chinese hamster cells 4
Alias:
2310057B22Rik
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促进3'突出末端单链DNA核酸酶活性。参与非同源末端连接的双链断裂修复；负调控保护端粒免受非同源末端连接的损害；以及形成包含端粒DNA的双分钟。在几个过程的上游或内部发挥作用，包括DNA代谢过程、造血作用和神经系统发育。位于染色体端粒区。是DNA依赖的蛋白激酶-DNA连接酶4复合物和ERCC4-ERCC1复合物的一部分。在头部、心脏和躯干表达。这个基因的人类同源物与多发性骨髓瘤有关。与人类的XRCC4（X射线修复互补组4）正交。[由基因组资源联盟，2022年4月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
Xrcc4 Genetics information (-)
GRCm39
Sequence Homology
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
References Literature
Title
PMID
Journal
Year
IF
