Rnf216 - ring finger protein 216

Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in several processes, including protein K48-linked ubiquitination; protein catabolic process; and regulation of defense response to virus by host. Predicted to act upstream of or within apoptotic process. Predicted to be located in cytosol; nucleoplasm; and synapse. Human ortholog(s) of this gene implicated in Gordon Holmes syndrome. Orthologous to human RNF216 (ring finger protein 216). [provided by Alliance of Genome Resources, Apr 2022]