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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Prkaa2 - protein kinase, AMP-activated, alpha 2 catalytic subunit
Alias:
A830082D05
AMPKalpha2
2310008I11Rik
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
激活AMP激活的蛋白激酶活性;染色质结合活性;组蛋白丝氨酸激酶活性。参与几个过程,包括自噬的调节;细胞器组织的调节;以及蛋白质修饰过程的调节。在几个过程的上游或内部发挥作用,包括细胞对前列腺素E刺激的响应;细胞对外源化合物刺激的响应;以及肌肉活动的响应。位于几个细胞组件中,包括胞质应激颗粒;树突;和神经元细胞体。在几个结构中表达,包括大脑;泌尿生殖系统;肠道;肺;和脊髓。这个基因的人类同源物与2型糖尿病有关。与人类PRKAA2(蛋白激酶AMP激活的催化亚基α2)正交。[由基因组资源联盟,2022年4月提供]
Related ID:
NCBI:108079
ENSEMBL:ENSMUSG00000028518
UNIPROT:Q8BRK8
Basic Information
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Transcripts
Exons
Length
MW (kDa)
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Reference
108079
2
9
80250 bp
62.02
8
28
Prkaa2 Genetics information (-)
GRCm39
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* This data comes from NCBI.
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