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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Grm5 - glutamate receptor, metabotropic 5
Alias:
Glu5R
Gprc1e
mGluR5
mGluR5b
6430542K11Rik
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
调节突触后膜电位和神经递质受体活性的G蛋白偶联受体活性,涉及调节突触胞浆钙离子浓度。参与几个过程,包括使用细胞内钙源的钙介导的信号传导;对淀粉样β的细胞反应;以及调节与年龄相关的行为下降的调节。位于几个细胞组件中,包括Schaffer collateral - CA1突触;神经元投影;和质膜。在中枢神经系统和视网膜中表达。用于研究精神分裂症。与人类的GRM5(谷氨酸代谢性受体5)正序同源。[由基因组资源联盟,2022年4月提供]
Related ID:
NCBI:108071
ENSEMBL:ENSMUSG00000049583
UNIPROT:Q3UVX5
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
108071
8
11
551060 bp
131.87
11
5
Grm5 Genetics information (+)
GRCm39
Sequence Homology
Transcripts & Proteins
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* This data comes from NCBI.
Gene Expression
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