Ddb2 - damage specific DNA binding protein 2

Predicted to enable DNA binding activity. Predicted to contribute to damaged DNA binding activity and ubiquitin-protein transferase activity. Acts upstream of or within pyrimidine dimer repair. Predicted to be located in cell junction and nucleoplasm. Predicted to be part of Cul4B-RING E3 ubiquitin ligase complex. Predicted to be active in nucleus. Used to study xeroderma pigmentosum group E. Human ortholog(s) of this gene implicated in xeroderma pigmentosum and xeroderma pigmentosum group E. Orthologous to human DDB2 (damage specific DNA binding protein 2). [provided by Alliance of Genome Resources, Apr 2022]