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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
人类
TRAF3IP2 - TRAF3 Interacting Protein 2
Alias:
ACT1
CIKS
C6orf2
C6orf4
C6orf5
C6orf6
CANDF8
PSORS13
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码一种蛋白质,该蛋白质参与调节Rel/NF-kappaB转录因子家族成员对细胞因子反应的调节。这些因子在响应病原体、炎症信号和应激的天然免疫中起着核心作用。这个基因产物与TRAF蛋白质(肿瘤坏死因子受体相关因子)和I-kappaB激酶或MAP激酶相互作用,以激活NF-kappaB或Jun激酶。已经识别出几种编码不同异构体的替代转录本。还识别了一种不编码蛋白质且反向转录的转录本。过表达这种转录本已被证明能降低至少一个编码蛋白质的转录本的表达,这表明它在表达这种基因中具有调节作用。[RefSeq,2009年8月提供]
Related ID:
NCBI:10758
ENSEMBL:ENSG00000056972
HGNC:1343
UNIPROT:O43734
OMIM:607043
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
10758
4
9
50498 bp
64.67
219
4
14
13
TRAF3IP2 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
No data available
Transcripts & Proteins
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#
Transcript
Length(nt)
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CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.
Gene Expression
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Cell-specific RNA expression
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Name
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Name
CAS Number
Status
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Link
No data available
References Literature
Title
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No Data Found!
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