Enables ubiquitin protein ligase activity. Involved in negative regulation of transcription, DNA-templated; proteasome-mediated ubiquitin-dependent protein catabolic process; and protein ubiquitination. Predicted to be located in cytosol. Predicted to be active in cytoplasm. Is expressed in limb and limb mesenchyme. Orthologous to human WWP1 (WW domain containing E3 ubiquitin protein ligase 1). [provided by Alliance of Genome Resources, Apr 2022]