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中文人类
MASP2 - MBL Associated Serine Protease 2
Alias:
sMAP
MAP-2
MAP19
MASP-2
MASP1P1
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这个基因编码丝氨酸蛋白酶S1家族的一个成员。编码的前体蛋白经过蛋白酶水解生成A和B链，两者异二聚体化形成成熟的蛋白酶。这种蛋白酶切割补体成分C2和C4，以生成补体系统凝集素途径中的C3转化酶。编码的蛋白酶还通过切割前凝血酶形成凝血酶，在凝血级联反应中发挥作用。心肌梗死和急性中风患者血清中编码蛋白的浓度降低。替代剪接导致多种转录变体，至少有一种编码一个经过蛋白酶水解的异构体。[由RefSeq提供，2016年2月]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
MASP2 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
