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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
人类
IGF2BP3 - Insulin Like Growth Factor 2 MRNA Binding Protein 3
Alias:
KOC
CT98
IMP3
KOC1
IMP-3
VICKZ3
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码的蛋白质主要存在于核仁中,可以与胰岛素样生长因子II前导3mRNA的5'UTR结合,可能在发育后期抑制胰岛素样生长因子II的翻译。编码的蛋白质含有几个KH结构域,这些结构域在RNA结合中起重要作用,已知参与RNA的合成和代谢。在第7染色体上存在一个假基因,其他染色体上还有推测的假基因。[由RefSeq,2008年7月提供]
Related ID:
NCBI:10643
ENSEMBL:ENSG00000136231
HGNC:28868
UNIPROT:O00425
OMIM:608259
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
10643
7
15
160283 bp
63.70
21
--
6
27
IGF2BP3 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
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Transcripts & Proteins
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* This data comes from NCBI.
Gene Expression
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