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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
人类
CENPF - Centromere Protein F
Alias:
CENF
hcp-1
CILD31
STROMS
PRO1779
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码一个与着丝点-动粒复合物相关的蛋白质。在间期G2期,该蛋白质是核矩阵的组成部分。在G2晚期,蛋白质与动粒结合,并在早期有丝分裂期保持这种关联。它定位在晚期有丝分裂中期和末期细胞的纺锤丝中央区和细胞内桥,随后被认为被降解。这个蛋白质的定位表明,它可能在有丝分裂过程中的染色体分离中发挥作用。它被认为形成同源二聚体或异源二聚体。在癌症或移植物抗宿主疾病患者中发现了针对这种蛋白质的自身抗体。[由RefSeq,2008年7月提供]
Related ID:
NCBI:1063
ENSEMBL:ENSG00000117724
HGNC:1857
UNIPROT:P49454
OMIM:600236
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
1063
3
20
61377 bp
357.53
533
1
6
25
CENPF Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
No data available
Transcripts & Proteins
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#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
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Interactions
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Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
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Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available
Related Drugs
Name
CAS Number
Status
Phase
Link
No data available
References Literature
Title
PMID
Journal
Year
IF
No Data Found!
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