人类

CENPF - Centromere Protein F

Alias:
CENF
hcp-1
CILD31
STROMS
PRO1779
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码一个与着丝点-动粒复合物相关的蛋白质。在间期G2期,该蛋白质是核矩阵的组成部分。在G2晚期,蛋白质与动粒结合,并在早期有丝分裂期保持这种关联。它定位在晚期有丝分裂中期和末期细胞的纺锤丝中央区和细胞内桥,随后被认为被降解。这个蛋白质的定位表明,它可能在有丝分裂过程中的染色体分离中发挥作用。它被认为形成同源二聚体或异源二聚体。在癌症或移植物抗宿主疾病患者中发现了针对这种蛋白质的自身抗体。[由RefSeq,2008年7月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
3
20
61377 bp
357.53
533
1
6
25

CENPF Genetics information (+)

GRCh38

Sequence Homology

Related Diseases and Mutations

#
Disease
Anatomical Category
Score
Mutations
No data available

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
Link
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Sequence
Comparison
Al agent
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