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中文人类
TXNIP - Thioredoxin Interacting Protein
Alias:
THIF
VDUP1
ARRDC6
HHCPA78
EST01027
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这个基因编码一种硫氧还蛋白结合蛋白，是α捕收蛋白家族的一员。硫氧还蛋白是一种主要的细胞氧化还原信号调节剂，保护细胞免受氧化应激。这种蛋白抑制硫氧还蛋白的抗氧化功能，导致活性氧物种的积累和细胞应激。这种蛋白还作为细胞代谢和内质网（ER）应激的调节剂发挥作用。这种蛋白也可能作为肿瘤抑制因子。交替剪接导致多个转录变异体。[RefSeq，2015年9月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
TXNIP Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
