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中文人类
CENPE - Centromere Protein E
Alias:
KIF10
CENP-E
MCPH13
PPP1R61
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中心体相关蛋白E（CENPE）是一种在细胞周期G2期积累的运动蛋白，类似于动力蛋白。与其他中心体相关蛋白不同，它在间期不存在，而在促细胞分裂期首先出现在染色体着丝点的中心区。这种蛋白质对于在促细胞分裂期染色体对齐过程中稳定捕获纺锤丝微管是必需的。该蛋白质还将染色体位置与微管的解聚活性耦合。选择性剪接导致多个转录变异体，编码不同的蛋白质异构体。[RefSeq，2014年11月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
CENPE Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
