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中文小鼠
Topors - topoisomerase I binding, arginine/serine-rich
Alias:
LUN
TP53BPL
p53BP3/LUN
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具有多种功能，包括DNA拓扑异构酶结合活性；抗原结合活性；以及泛素样蛋白转移酶活性。通过p53类介质响应DNA损伤，在内在凋亡信号通路中位于上游或内部；DNA模板的转录正向调节；以及细胞群增殖的调节。位于纤毛基体；细胞核；和光感受器连接纤毛。在皮肤中表达。该基因的人类同源物与视网膜色素变性31有关。与人类TOPORS（TOP1结合精氨酸/丝氨酸丰富蛋白，E3泛素连接酶）正交。[由基因组资源联盟，2022年4月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
Topors Genetics information (-)
GRCm39
Sequence Homology
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
References Literature
Title
PMID
Journal
Year
IF
