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中文人类
SLCO1B1 - Solute Carrier Organic Anion Transporter Family Member 1B1
Alias:
LST1
HBLRR
LST-1
OATP2
OATPC
OATP-C
OATP1B1
SLC21A6
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这个基因编码有机阴离子转运蛋白家族中的肝脏特异性的成员。编码的蛋白质是一种介导钠离子不依赖的摄取多种内源性化合物包括胆红素、17-β-葡萄糖醛酸酯雌二醇和白三烯C4的跨膜受体。这个蛋白质也参与从血液中移除药物化合物如他汀类药物、溴磺酚酞和利福平进入肝细胞。编码这个蛋白质的基因的变异与转运蛋白功能受损相关。[RefSeq,2009年3月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
SLCO1B1 Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
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Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
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Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
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Residues
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Score
Related Mouse Models
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Name
MGI
Strain of Origin
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CAS Number
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Link
References Literature
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