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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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人类
ERN2 - Endoplasmic Reticulum To Nucleus Signaling 2
Alias:
IRE1b
IRE2p
hIRE2p
IRE1-BETA
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
具有多种功能,包括ATP结合活性;镁离子结合活性;以及蛋白丝氨酸/苏氨酸激酶活性。参与多个过程,包括凋亡染色体凝缩;DNA模板转录的负调控;和rRNA分解代谢过程。预测位于内质网膜和内质网质量控制腔室中。预测是膜的整合成分。预测是IRE1-TRAF2-ASK1复合物的一部分。[由基因组资源联盟,2022年4月提供]
Related ID:
NCBI:10595
ENSEMBL:ENSG00000134398
HGNC:16942
UNIPROT:Q76MJ5
OMIM:604034
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
10595
6
22
22913 bp
102.48
32
--
6
4
ERN2 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
No data available
Transcripts & Proteins
Table View
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#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Reset
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available
Related Drugs
Name
CAS Number
Status
Phase
Link
No data available
References Literature
Title
PMID
Journal
Year
IF
No Data Found!
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