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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Prkaa1 - protein kinase, AMP-activated, alpha 1 catalytic subunit
Alias:
AMPKalpha1
C130083N04Rik
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
激活AMP激活的蛋白激酶活性;染色质结合活性;组蛋白丝氨酸激酶活性。参与几个过程,包括基因表达的调节;细胞器组织的调节;以及蛋白质修饰过程的调节。在几个过程的上游或内部发挥作用,包括细胞对前列腺素E刺激的响应;骨骼肌组织发育的正调控;以及肽酰丝氨酸磷酸化的调节。位于几个细胞组件中,包括轴突;树突;和神经元细胞体。在几个结构中表达,包括大脑;早期概念期;未来大脑;和脊髓。这个基因的人类正交蛋白涉及亨廷顿病;乳腺癌;结肠癌;和肺癌。与人类PRKAA1(蛋白激酶AMP激活的催化亚基α1)正交。[由基因组资源联盟,2022年4月提供]
Related ID:
NCBI:105787
ENSEMBL:ENSMUSG00000050697
UNIPROT:Q5EG47
Basic Information
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Length
MW (kDa)
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Reference
105787
3
9
38740 bp
63.93
9
31
Prkaa1 Genetics information (+)
GRCm39
Sequence Homology
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* This data comes from NCBI.
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