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Prkaa1 - protein kinase, AMP-activated, alpha 1 catalytic subunit

Alias:
AMPKalpha1
C130083N04Rik
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
激活AMP激活的蛋白激酶活性;染色质结合活性;组蛋白丝氨酸激酶活性。参与几个过程,包括基因表达的调节;细胞器组织的调节;以及蛋白质修饰过程的调节。在几个过程的上游或内部发挥作用,包括细胞对前列腺素E刺激的响应;骨骼肌组织发育的正调控;以及肽酰丝氨酸磷酸化的调节。位于几个细胞组件中,包括轴突;树突;和神经元细胞体。在几个结构中表达,包括大脑;早期概念期;未来大脑;和脊髓。这个基因的人类正交蛋白涉及亨廷顿病;乳腺癌;结肠癌;和肺癌。与人类PRKAA1(蛋白激酶AMP激活的催化亚基α1)正交。[由基因组资源联盟,2022年4月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
3
9
38740 bp
63.93
9
31

Prkaa1 Genetics information (+)

GRCm39

Sequence Homology

Transcripts & Proteins

Table View
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#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Sequence
Comparison
Al agent
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