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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
人类
TADA3 - Transcriptional Adaptor 3
Alias:
ADA3
NGG1
hADA3
STAF54
TADA3L
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
DNA结合的转录激活蛋白通过与结合在基本启动子的转录机制以及适配蛋白相互作用,提高转录速率,可能是通过核小体的乙酰化和去稳定化。这个基因编码的蛋白质是一种转录激活适配蛋白,是组蛋白乙酰转移酶(HAT)共激活物复合物的组成部分,该复合物在染色质调节和细胞周期进展中起着关键作用。与复合物的其他成分一起,这个蛋白质将结合在特定启动子的转录激活子连接到组蛋白乙酰化和转录机制。这个蛋白质也参与稳定和激活p53肿瘤抑制蛋白,该蛋白在细胞对DNA损伤的反应中起作用。交替剪接导致这个基因的多个转录变异体。[RefSeq提供,2013年5月]
Related ID:
NCBI:10474
ENSEMBL:ENSG00000171148
HGNC:19422
UNIPROT:O75528
OMIM:602945
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
10474
3
9
13045 bp
48.90
13
--
3
14
TADA3 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
No data available
Transcripts & Proteins
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#
Transcript
Length(nt)
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CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
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Cell-specific RNA expression
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Type
Name
MGI
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Mutations
No data available
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Name
CAS Number
Status
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Link
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References Literature
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