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中文人类
GPNMB - Glycoprotein Nmb
Alias:
NMB
HGFIN
PLCA3
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这个基因编码的蛋白质是一种I型跨膜糖蛋白，与pMEL17前体，一种黑色素细胞特异性蛋白质具有同源性。GPNMB在低转移性人类黑色素瘤细胞系和异种移植中显示表达，但在高转移性细胞系中不显示表达。GPNMB可能参与生长延迟和降低转移潜力。已发现这个基因有两个编码不同异构体的转录变异体。[由RefSeq，2008年7月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
GPNMB Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
