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中文人类
NDRG1 - N-myc Downstream Regulated 1
Alias:
GC4
RTP
DRG1
NDR1
NMSL
TDD5
CAP43
CMT4D
DRG-1
HMSNL
RIT42
TARG1
PROXY1
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这个基因是N-myc下调基因家族的成员，属于α/β水解酶超家族。这个基因编码的蛋白质是一种参与应激反应、激素反应、细胞生长和分化的细胞质蛋白质。这个编码的蛋白质是p53介导的caspase激活和凋亡所必需的。这个基因的突变是导致Charcot-Marie-Tooth疾病4D型的原因，并且这个基因的表达可能是几种癌症的预后指标。已经观察到了这个基因的替代剪接转录变体，编码多种异构体。[由RefSeq提供，2012年5月]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
NDRG1 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
