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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
人类
DLC1 - DLC1 Rho GTPase Activating Protein
Alias:
HP
ARHGAP7
STARD12
p122-RhoGAP
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码一个GTP酶激活蛋白(GAP),是rhoGAP家族蛋白质的成员,这些蛋白质在调节小GTP结合蛋白质中发挥作用。GAP家族蛋白质参与调节细胞过程的信号传导途径,这些过程涉及细胞骨架的变化。这个基因作为肿瘤抑制基因在多种常见癌症中发挥作用,包括前列腺癌、肺癌、结肠癌和乳腺癌。已经发现这个基因由于可选的启动子和可选的剪接而有多种转录变异体。[由RefSeq,2010年4月提供]
Related ID:
NCBI:10395
ENSEMBL:ENSG00000164741
HGNC:2897
UNIPROT:Q96QB1
OMIM:604258
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
10395
26
18
521260 bp
170.59
298
1
6
19
DLC1 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
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No data available
Transcripts & Proteins
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Transcript
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Length(aa)
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* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
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Cell-specific RNA expression
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References Literature
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