人类

DLC1 - DLC1 Rho GTPase Activating Protein

Alias:
HP
ARHGAP7
STARD12
p122-RhoGAP
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码一个GTP酶激活蛋白(GAP),是rhoGAP家族蛋白质的成员,这些蛋白质在调节小GTP结合蛋白质中发挥作用。GAP家族蛋白质参与调节细胞过程的信号传导途径,这些过程涉及细胞骨架的变化。这个基因作为肿瘤抑制基因在多种常见癌症中发挥作用,包括前列腺癌、肺癌、结肠癌和乳腺癌。已经发现这个基因由于可选的启动子和可选的剪接而有多种转录变异体。[由RefSeq,2010年4月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
26
18
521260 bp
170.59
298
1
6
19

DLC1 Genetics information (-)

GRCh38

Sequence Homology

Related Diseases and Mutations

#
Disease
Anatomical Category
Score
Mutations
No data available

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
Link
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Comparison
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