人类

ANAPC10 - Anaphase Promoting Complex Subunit 10

Alias:
DOC1
APC10
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
ANAPC10是促进细胞周期进展所必需的泛素蛋白连接酶APC(或称为cyclosome)的核心亚基。APC通过泛素化securin(PTTG1;MIM 604147)和激活细胞周期蛋白依赖性激酶1(CDK1;MIM 116940)的激活亚基细胞周期蛋白B(CCNB1;MIM 123836)来启动姐妹染色单体分离并触发有丝分裂的结束。这一总结由Wendt等人于2001年发表[PubMed 11524682]。由OMIM于2011年2月提供。

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
20
5
103997 bp
21.25
4
--
3
12

ANAPC10 Genetics information (-)

GRCh38

Sequence Homology

Related Diseases and Mutations

#
Disease
Anatomical Category
Score
Mutations
No data available

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
Link
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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