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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
人类
CCL26 - C-C Motif Chemokine Ligand 26
Alias:
IMAC
TSC-1
MIP-4a
SCYA26
MIP-4alpha
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因是位于染色体7q臂上的两个Cys-Cys(CC)细胞因子基因之一。细胞因子是一类参与免疫调节和炎症过程的分泌性蛋白质。CC细胞因子是以两个相邻的半胱氨酸为特征的蛋白质。这个基因编码的细胞因子显示了对正常外周血嗜酸性粒细胞和嗜碱粒细胞的趋化活性。这种蛋白质还具有抗菌活性,对肺炎链球菌、金黄色葡萄球菌、不能分型的大流感嗜血杆菌和绿脓杆菌具有抗菌作用。这个基因的产品是三种相关趋化因子中的一种,这些趋化因子特异性地激活趋化因子受体CCR3。这种趋化因子可能有助于特应性疾病中嗜酸性粒细胞的积累。[由RefSeq,2020年7月提供]
Related ID:
NCBI:10344
ENSEMBL:ENSG00000006606
HGNC:10625
UNIPROT:Q9Y258
OMIM:604697
Basic Information
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Exons
Length
MW (kDa)
Mutations
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Reference
10344
3
3
22074 bp
10.65
5
--
4
8
CCL26 Genetics information (-)
GRCh38
Sequence Homology
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* This data comes from NCBI.
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