人类

CCL26 - C-C Motif Chemokine Ligand 26

Alias:
IMAC
TSC-1
MIP-4a
SCYA26
MIP-4alpha
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因是位于染色体7q臂上的两个Cys-Cys(CC)细胞因子基因之一。细胞因子是一类参与免疫调节和炎症过程的分泌性蛋白质。CC细胞因子是以两个相邻的半胱氨酸为特征的蛋白质。这个基因编码的细胞因子显示了对正常外周血嗜酸性粒细胞和嗜碱粒细胞的趋化活性。这种蛋白质还具有抗菌活性,对肺炎链球菌、金黄色葡萄球菌、不能分型的大流感嗜血杆菌和绿脓杆菌具有抗菌作用。这个基因的产品是三种相关趋化因子中的一种,这些趋化因子特异性地激活趋化因子受体CCR3。这种趋化因子可能有助于特应性疾病中嗜酸性粒细胞的积累。[由RefSeq,2020年7月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
3
3
22074 bp
10.65
5
--
4
8

CCL26 Genetics information (-)

GRCh38

Sequence Homology

Related Diseases and Mutations

#
Disease
Anatomical Category
Score
Mutations
No data available

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
Link
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Comparison
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