人类

TLR6 - Toll Like Receptor 6

Alias:
CD286
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码的蛋白质是Toll样受体(TLR)家族的一员,在病原体识别和天然免疫激活中起基本作用。TLRs从果蝇到人类高度保守,并在结构和功能上相似。它们识别感染性生物上表达的病原体相关分子模式(PAMPs),并调节产生有效免疫发展所需的细胞因子。各种TLR以不同的表达模式表达。这个受体与TLR2功能相互作用,以调节对细菌脂质蛋白的细胞反应。编码蛋白质的细胞外结构域中的Ser249Pro多态性可能与某些人群哮喘病率的增加有关。[RefSeq,2011年1月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
8
2
45494 bp
91.88
40
--
8
9

TLR6 Genetics information (-)

GRCh38

Sequence Homology

Related Diseases and Mutations

#
Disease
Anatomical Category
Score
Mutations
No data available

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
Link
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Comparison
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