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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
人类
TLR6 - Toll Like Receptor 6
Alias:
CD286
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Description
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码的蛋白质是Toll样受体(TLR)家族的一员,在病原体识别和天然免疫激活中起基本作用。TLRs从果蝇到人类高度保守,并在结构和功能上相似。它们识别感染性生物上表达的病原体相关分子模式(PAMPs),并调节产生有效免疫发展所需的细胞因子。各种TLR以不同的表达模式表达。这个受体与TLR2功能相互作用,以调节对细菌脂质蛋白的细胞反应。编码蛋白质的细胞外结构域中的Ser249Pro多态性可能与某些人群哮喘病率的增加有关。[RefSeq,2011年1月提供]
Related ID:
NCBI:10333
ENSEMBL:ENSG00000174130
HGNC:16711
UNIPROT:Q9Y2C9
OMIM:605403
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
10333
8
2
45494 bp
91.88
40
--
8
9
TLR6 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
No data available
Transcripts & Proteins
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#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
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Cell-specific RNA expression
Organ
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Interactions
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Related Mouse Models
Type
Name
MGI
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No data available
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CAS Number
Status
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Link
No data available
References Literature
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Journal
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IF
No Data Found!
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