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中文人类
CDKN2D - Cyclin Dependent Kinase Inhibitor 2D
Alias:
p19
INK4D
p19-INK4D
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这个基因编码的蛋白质是周期蛋白依赖性激酶抑制剂INK4家族的成员。该蛋白质已被证明能与CDK4或CDK6形成稳定的复合物，防止CDK激酶的激活，从而作为控制细胞周期G1进展的细胞生长调节因子。发现这个基因的转录本的丰度以细胞周期依赖的方式振荡，在G1中期表达最低，在S期表达最大。这个蛋白质的负调控参与抑制神经元增殖和精母细胞的增殖。已经报道了这个基因的两个可变剪接变异体，它们编码相同的蛋白质。[由RefSeq，2008年7月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
CDKN2D Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
