人类

LILRB2 - Leukocyte Immunoglobulin Like Receptor B2

Alias:
ILT4
LIR2
CD85D
ILT-4
LIR-2
MIR10
MIR-10
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因是白细胞免疫球蛋白样受体(LIR)家族的成员,位于染色体19q13.4区域的基因簇中。编码的蛋白质属于LIR受体B类亚家族,包含两个或四个细胞外免疫球蛋白结构域,一个跨膜结构域,以及两个到四个细胞质免疫受体酪氨酸抑制基序(ITIMs)。受体在免疫细胞上表达,与抗原呈递细胞上的MHC I类分子结合,并传递负信号,抑制免疫应答的刺激。它被认为控制炎症反应和细胞毒性,以帮助聚焦免疫应答并限制自体反应性。已发现这个基因的多个转录变异体,编码不同的异构体。[由RefSeq,2008年7月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
6
14
7299 bp
65.00
49
--
6
14

LILRB2 Genetics information (-)

GRCh38

Sequence Homology

Related Diseases and Mutations

#
Disease
Anatomical Category
Score
Mutations
No data available

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
Link
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Comparison
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