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中文人类
UBE4B - Ubiquitination Factor E4B
Alias:
E4
UFD2
HDNB1
UBOX3
UFD2A
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泛素对蛋白质的修饰是将异常或寿命短的蛋白质作为靶标进行降解的重要细胞机制。泛素化涉及至少三类酶：泛素激活酶，或E1s，泛素连接酶，或E2s，和泛素蛋白质连接酶，或E3s。此基因编码一个额外的连接因子E4，参与多泛素链的组装。此基因也是神经母细胞瘤肿瘤抑制基因的最强候选者。此基因发现了编码不同异构体的可变剪接转录变体。[由RefSeq提供，2008年7月]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
UBE4B Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
