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中文人类
RAMP1 - Receptor Activity Modifying Protein 1
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这个基因编码的蛋白质是RAMP家族中的一员，这些单跨膜域蛋白质被称为受体(降钙素)活性调节蛋白(RAMP)。RAMP是I型跨膜蛋白，具有细胞外N端和细胞质C端。RAMP是将降钙素受体样受体(CRLR)运输到质膜所必需的。CRLR是一种具有7个跨膜结构的受体，可以根据RAMP家族成员的表达情况作为降钙素基因相关肽(CGRP)受体或肾上腺髓质素受体发挥作用。在存在这种(RAMP1)蛋白质的情况下，CRLR作为CGRP受体发挥作用。RAMP1蛋白质参与CGRP受体的末端糖基化、成熟和向细胞表面的呈现。可变剪接产生多种编码不同异形体的转录变异体。[RefSeq，2015年4月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
RAMP1 Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
