Mapkapk3 - mitogen-activated protein kinase-activated protein kinase 3

Predicted to enable calmodulin binding activity; mitogen-activated protein kinase binding activity; and protein serine/threonine kinase activity. Involved in macropinocytosis; response to lipopolysaccharide; and toll-like receptor signaling pathway. Predicted to be located in nucleoplasm. Predicted to be active in cytoplasm and nucleus. Is expressed in several structures, including alimentary system; naris; skin; urinary system; and ventral grey horn. Human ortholog(s) of this gene implicated in patterned macular dystrophy 3. Orthologous to human MAPKAPK3 (MAPK activated protein kinase 3). [provided by Alliance of Genome Resources, Apr 2022]