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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
人类
DENND4A - DENN Domain Containing 4A
Alias:
IRLB
MYCPBP
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码一个含有DENN结构域的蛋白质,可能作为特异地激活ras相关蛋白Rab-10的鸟苷酸交换因子发挥作用。这个蛋白质还包含一个干扰素刺激反应元件结合结构域,可能参与调节v-myc禽成髓细胞白血病病毒(MYC)癌基因。交替剪接导致多个转录变异体。这个基因的一个假基因位于染色体8上。[RefSeq,2016年3月提供]
Related ID:
NCBI:10260
ENSEMBL:ENSG00000174485
HGNC:24321
UNIPROT:Q7Z401
OMIM:600382
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
10260
28
33
133171 bp
209.24
45
--
2
15
DENND4A Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
No data available
Transcripts & Proteins
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#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
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Interactions
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Acting
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Score
No data available
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available
Related Drugs
Name
CAS Number
Status
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Link
No data available
References Literature
Title
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Journal
Year
IF
No Data Found!
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