Adamts13 - ADAM metallopeptidase with thrombospondin type 1 motif, 13

Enables endopeptidase activity. Involved in several processes, including cellular response to cytokine stimulus; cellular response to lipopolysaccharide; and response to potassium ion. Located in extracellular space. Biomarker of cholestasis and non-alcoholic fatty liver disease. Human ortholog(s) of this gene implicated in thrombotic thrombocytopenic purpura. Orthologous to human ADAMTS13 (ADAM metallopeptidase with thrombospondin type 1 motif 13). [provided by Alliance of Genome Resources, Apr 2022]