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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
大鼠
Kmt2b - lysine methyltransferase 2B
Alias:
Mll4
Wbp7
RGD1308331
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
预测能够激活组蛋白甲基转移酶活性(特异性的H3-K4);未甲基化的CpG结合活性;和锌离子结合活性。预测参与组蛋白H3-K4的二甲基化;组蛋白H3-K4的单甲基化;和DNA模板的正调控转录。预测在几个过程的上游或内部发挥作用,包括依赖DNA甲基化的异染色质组装;雌性配子的生成;和组蛋白H3-K4的三甲基化。预测位于细胞核中。预测是组蛋白甲基转移酶复合物的一部分。该基因的人类同源物与结直肠癌;肌张力障碍;和肝细胞癌有关。与人类KMT2B(赖氨酸甲基转移酶2B)正交。[由基因组资源联盟,2022年4月提供]
Related ID:
NCBI:102550344
ENSEMBL:ENSRNOG00000055525
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
102550344
3
37
19288 bp
Unknown
8
--
Kmt2b Genetics information (-)
mRatBN7.2
Sequence Homology
Transcripts & Proteins
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* This data comes from NCBI.
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