人类

SPRY2 - Sprouty RTK Signaling Antagonist 2

Alias:
IGAN3
hSPRY2
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码一个属于sprouty家族的蛋白质。编码的蛋白质含有羧基端半胱氨酸丰富的结构域,对受体酪氨酸激酶信号蛋白的抑制活性是必需的,并且是生长因子刺激蛋白质向膜皱襞移动所必需的。在原真皮内皮细胞中,这个基因在响应成纤维细胞生长因子2的情况下被暂时上调。这个蛋白质间接参与了对成纤维细胞生长因子2信号的非细胞自主抑制效应。这个蛋白质与Cas-Br-M(小鼠)外显性逆转录病毒转化序列相互作用,并可以作为表皮生长因子受体/有丝分裂原激活的蛋白质激酶信号的双模式调节剂。这个蛋白质可能在肺发育过程中肺泡分支中发挥作用,如类似的小鼠蛋白质所示。[由RefSeq,2008年7月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
4
2
5151 bp
34.69
12
1
6
14

SPRY2 Genetics information (-)

GRCh38

Sequence Homology

Related Diseases and Mutations

#
Disease
Anatomical Category
Score
Mutations
No data available

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
Link
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Mutation Direct
Sequence
Comparison
Al agent
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