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中文人类
CDK8 - Cyclin Dependent Kinase 8
Alias:
K35
IDDHBA
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这个基因编码一个细胞周期蛋白依赖性蛋白激酶（CDK）家族的成员。CDK家族成员被认为是细胞周期进程的重要调节因子。这个激酶及其调节亚单位，细胞周期蛋白C，是中介体转录调节复合体的组成部分，通过磷酸化RNA聚合酶II的最大亚单位的羧基端域参与转录激活和抑制。这个激酶通过靶向通用转录起始因子IIH的细胞周期依赖性激酶7亚单位来调节转录，从而在中介体复合体与基本的转录机制之间建立联系。已经发现了这个基因的多个假基因。选择性剪接产生了多个转录变异体。[RefSeq，2016年10月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
CDK8 Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
