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中文人类
MSLN - Mesothelin
Alias:
MPF
SMRP
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这个基因编码一个前原蛋白，该前原蛋白在蛋白水解过程中被加工成两个蛋白质产物，巨核细胞增强因子和中皮素。巨核细胞增强因子作为一种细胞因子，可以刺激骨髓巨核细胞的集落形成。中皮素是一种糖磷脂酰肌醇锚定的细胞表面蛋白，可能作为细胞粘附蛋白发挥作用。这个蛋白在上皮间皮瘤、卵巢癌以及特定的鳞状细胞癌中过度表达。可变剪接导致多个转录变异体，至少其中一个编码一种经过蛋白水解加工的异构体。[由RefSeq，2016年2月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
MSLN Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
